Helitrons , the Eukaryotic Rolling-circle Transposable Elements
نویسندگان
چکیده
منابع مشابه
Transposable elements and the evolution of eukaryotic genomes.
W hen transposable elements (TEs) were discovered in maize by Barbara McClintock 50 years ago they were regarded as a curiosity; now they are known to be the most abundant component of probably all eukaryotic genomes. They account for almost 50% of the human genome and 70% of the genomes of some grass species, including maize. As such, they make up the vast majority of the output of genome sequ...
متن کاملTransposable elements and the evolution of eukaryotic complexity.
Eukaryotic transposable elements are ubiquitous and widespread mobile genetic entities. These elements often make up a substantial fraction of the host genomes in which they reside. For example, approximately 1/2 of the human genome was recently shown to consist of transposable element sequences. There is a growing body of evidence that demonstrates that transposable elements have been major pl...
متن کاملThe Discovery of Rolling Circle Amplification and Rolling Circle Transcription.
Nucleic acid amplification is a hugely important technology for biology and medicine. While the polymerase chain reaction (PCR) has been highly useful and effective, its reliance on heating and cooling cycles places some constraints on its utility. For example, the heating step of PCR can destroy biological molecules under investigation and heat/cool cycles are not applicable in living systems....
متن کاملEukaryotic Transposable Elements: Teaching Old Genomes New Tricks
When transposable elements were discovered in maize by Barbara McClintock over 50 years ago they were regarded as a curiosity—now they are known to be to the most abundant component of probably all eukaryotic genomes. As such, they make up the vast majority of the output of genome sequencing projects. The availability of so much new information has fueled a revolution in their analysis and stud...
متن کاملHelitrons: Enigmatic abductors and mobilizers of host genome sequences
Helitrons are a recently discovered superfamily of eukaryotic transposable elements. They are known for their ability to capture and mobilize gene fragments and, in turn, significantly contribute to the lack of gene colinearity widely reported among different maize inbred lines. As judged by present evidence, Helitrons differ fundamentally from Class I and Class II families of transposable elem...
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ژورنال
عنوان ژورنال: Microbiology Spectrum
سال: 2015
ISSN: 2165-0497
DOI: 10.1128/microbiolspec.mdna3-0049-2014